Ardisianon
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Ardisianone is a component with an alkyl benzoquinone structure that can be isolated from Ardisia virens Kurz and Ardisia compressa tea extract. Ardisianone exhibits potent antileukemic activity, particularly against HL-60 cells, with IC50 values of 1.87 μM (24 h) and 1.67 μM (48 h) . Ardisianone induces caspase-dependent apoptosis and triggers pyroptosis. Ardisianone can be used for the study of acute myeloid leukemia (AML) [1].
66398-68-3
12352211
Apoptosis; Pyroptosis
Apoptosis; Immunology/Inflammation
Cancer-programmed cell death
Cancer
CCCCCCCCCCCCC[C@@H](OC(C)=O)CC(C(C(OC)=C1)=O)=CC1=O
C24H38O5
406.56
[1]Leu WJ, et al. Antileukemic Natural Product Induced Both Apoptotic and Pyroptotic Programmed Cell Death and Differentiation Effect. Int J Mol Sci. 2021 Oct 18;22 (20) :11239.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N12641/
Natural Products
No Development Reported
Beschrijving
Ardisianone is a component with an alkyl benzoquinone structure that can be isolated from Ardisia virens Kurz and Ardisia compressa tea extract. Ardisianone exh
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