Arecaidine (hydrochloride) (standaard)

Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake[1][2].

6018-28-6

12352005

GABA Receptor

Membrane Transporter/Ion Channel; Neuronal Signaling

Neurological Disease

O=C(C1=CCCN(C)C1)O.[H]Cl

C7H12ClNO2

177.63

[1]D Lodge, et al. Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system. Brain Res. 1977 Nov 18;136 (3) :513-22.|[2]Valerie Voigt, et al. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1) . J Pharm Pharmacol. 2013 Apr;65 (4) :582-90.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N2368AR/

Reference Standards