ARF6 Antilichaam - middengebied: FITC (ARP54598_P050-FITC)

ADP-ribosylation factor 6

DKFZp564M0264

382

P62330

NP_001654

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human ARF6

ARF6 is a member of the human ARF family, which is part of the RAS superfamily. They are small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF6 is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; LSB5; GGA1; STAU1; EGFR; CYTH1; CYTH2; GNAQ; FN1; VCP; APP; RAB11FIP3; RAB11FIP4; RAB11FIP5; USP6; IKBKG; GGA3; ITSN1; ASAP1; FBXO8; MEPCE; RUVBL2; ASAP3; MPP5; ZNF709; EXOC5; ARFIP2; AP3D1; PIP5K1C; ASAP2; AP3B1; PIP5K1A; PLD1; AP1B1; EZR; CHRM3; CA

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

ARF6 is strongly supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

20kDa

Karim, Z.A., (2008) J. Biol. Chem. 283 (18), 11995-12003

Wet Ice

175

ARF6

ARF6

Rabbit

ADP-ribosylation factor 6

NM_001663

REMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSG