ARFGAP1 Antilichaam - middengebied: Biotine (ARP57149 P050-Biotine)

ADP-ribosylation factor GTPase activating protein 1

ARF1GAP, HRIHFB2281

55738

Q8N6T3

NP_060679

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human ARFGAP1

The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1) . The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.

KRTAP10-9; KRTAP9-2; KRTAP3-2; GABARAPL2; GRN; FOS; TRIM23; UBC; RPL22; HK1; RAD52; RPL11; RFC3; PRKACB; APOE; APOC3; APOB; ASB10; RASIP1; RAB23; COPS5; MED27; REEP5; APP; LRRK2; MAP1LC3B; TK1; SMN1; TMED2; CYTH2; COPA; CSNK1D; RGS2; KDELR1; ARF1

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

45kDa

Wet Ice

406

ARFGAP1

ARFGAP1

Rabbit

ADP-ribosylation factor GTPase-activating protein 1

NM_018209

GQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFGNTPPPQKKEDDFL