ARHGDIA Antilichaam, KO gevalideerd

This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

396

P52565

Human, Mouse, Rat, Monkey

Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human ARHGDIA (NP_001172006.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cell Cycle, Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 25kDa

IgG

ARHGDIA

COS7

PC-12

Mouse lung

Mouse spleen

Mouse kidney

Rho GDP dissociation inhibitor (GDI) alpha

Homo sapiens

ARHGDIA, RHOGDI-1, RHOGDI, Rho GDP dissociation inhibitor (GDI) alpha, MGC117248, GDIA1

WB, IF

Liquid