ARRB2 Antilichaam

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

409

P32121

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 165-394 of human ARRB2 (NP_945355.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

IgG

ARRB2

Arrestin, beta 2

Homo sapiens

ARRB2, ARB2, ARR2, DKFZp686L0365, BARR2

WB, IHC, IF

Liquid