ARSA Antilichaam - middengebied: FITC (ARP54529_P050-FITC)

Arylsulfatase A

ASA, MLD

410

P15289

NP_001078896

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human ARSA

ARSA hydrolyzes cerebroside sulfate. Defects in ARSA are a cause of leukodystrophy metachromatic (MLD) .The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.

TRIP13; PPIC; CETN2; CLEC4G; ARSA; GAL3ST1; BMPR2; CTSL

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 79%; Dog: 92%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 92%; Rabbit: 79%; Rat: 85%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

52kDa

Saito, S., (2008) Mol. Genet. Metab. 93 (4), 419-425

Wet Ice

507

ARSA

ARSA

Rabbit

Arylsulfatase A

NM_001085427

KQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPH