ARSB Antilichaam

Aryl sulfatase B (ARSB) forms a homodimer that hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate (1) . ARSB localizes to the lysozyme as well as to the extracellular matrix (2) . Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B (3), and can be treated with exogenous ARSB (4) .

411

P15848

NP_000037

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

ARSB Antibody is affinity chromatography purified via peptide column.

Cat. No. 1412 - Mouse Lung Tissue Lysate

1 mg/mL

ARSB Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

ARSB antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

ARSB antibody is human, mouse and rat reactive. At least two isoforms of ARSB are known to exist; this antibody only recognizes the longest isoform.

ARSB

Cat. No. 1412 - Mouse Cerebellum Tissue Lysate

Cat. No. 10-101 - Human Lung Tissue Slide

Arylsulfatase B

Homo sapiens

Wasserman SI and Austen KF. Arylsulfatase B of human lung. Isolation, characterization, and interaction with slow-reacting substance of anaphylaxis. J. Clin. Invest. 1976; 57:738-44.

Mitsunaga-Nakatsubo K, Kusunoki S, Kawakami H, et al. Cell-surface arylsulfatase A and B on sinusoidal endothelial cells, hepatocytes, and Kupffer cells in mammalian livers. Med. Mol. Morphol. 2009; 42:63-9.

Valayannopoulos V, Nicely H, Harmatz P, et al. Mucopolysaccharidosis VI. Orphanet. J. Rare Dis. 2010; 5:5.

Harmatz P, Whitley CB, Waber L, et al. Enzyme replacement therapy in mucopolysaccharidosis VI (Maroteaux-Lamy syndrome) . J. Pediatr. 2004; 144:574-80.

ARSB Antibody : ASB, G4S, MPS6, Arylsulfatase B, N-acetylgalactosamine-4-sulfatase, ASB

ELISA, WB, IHC-P, IF

38569405

Liquid