ART0380
Gecertificeerd

ART0380

Catalog #: C02002-01
Maat: 5 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

CAS Number

2267316-76-5

Synonyms

IACS-030380

SKU

C02002-5mg

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Additionnal Information

ART0380 (IACS-030380) is a potent and selective, orally bioavailable inhibitor of ATR kinase, with an IC50 of 51.7 nM effectively inhibiting the enzyme activity of the ATR-ATRIP complex. It functions as an ATP-competitive inhibitor, binding to the ATP pocket of ATR, where ATP would typically bind. It interacts with the hinge through its morpholine oxygen and occupies the ribose pocket with a sulfoximine group. It also exhibits antitumor activity.

Beschrijving

ART0380 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamART0380
Categorie
Beschikbare grootte5 mg
CatalogusnummerC02002-01