
ARV-110
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ARV-110 is a CRBN-based PROTAC protein degrader that recruits the cereblon-containing E3 ubiquitin ligase to direct the proteasomal degradation of the androgen receptor (AR) . It selectively degrades wild-type AR and most clinically relevant mutants with low nM potency.1 ARV-110 is the first PROTAC to enter the clinic.2 Analytical methods suitable for pharmacokinetic studies have been developed.3
Unconjugated
Pale yellow solid
-20°C
Beschrijving
ARV-110 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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