ASB6 Antilichaam - middengebied: HRP (ARP53352 P050-HRP)

Ankyrin repeat and SOCS box containing 6

FLJ20548, MGC1024

140459

Q9NWX5

NP_060343

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human ASB6

ASB6 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.

FAM9B; L3MBTL3; RNF41; CADPS2; HIF1AN; ASB3; RNF7; CUL5; TCEB2; HSPB1; FGG; FGB; FGA; SLC25A5; OGFOD1; MCTS1; PROSC; XPNPEP1; EZR; HDGF; FH; ATIC; HSP90AA1; APP; UBD; UBC; DCUN1D1; COPS5; CUL4B; TCEB1; ELAVL1; SH2B2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

ASB6 is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

46kDa

Wilcox, A., (2004) J. Biol. Chem. 279 (37), 38881-38888

Wet Ice

421

ASB6

ASB6

Rabbit

Ankyrin repeat and SOCS box protein 6

NM_017873

LKMAELGLTRAADVLLRHGANLNFEDPVTYYTALHIAVLRNQPDMVELLV