ASCC1 Antilichaam

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF) . The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

51008

Q8N9N2

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ASCC1 (NP_001185727.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

Rat pancreas

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 46kDa

IgG

ASCC1

Activating signal cointegrator 1 complex subunit 1

Homo sapiens

ASC1p5CGI-18, SMABF2, p5activating signal cointegrator 1 complex subunit 1, ASC-1 complex subunit P5trip4 complex subunit p50

WB, IF

Liquid