Asenapine-13C, d3 (maleaat)

Asenapine-13C, d3 Maleate is the deuterium labeled and 13C-Asenapine Maleate. Asenapine (Org 5222) Maleate, an atypical antipsychotic, is an antagonist of serotonin receptors (pKi: 8.4-10.5), adrenoceptors (pKi: 8.9-9.5), dopamine receptors (pKi: 8.9-9.4) and histamine receptors (pKi: 8.2-9.0). Asenapine Maleate can be used in the research of schizophrenia and bipolar disorder[1][2].

Org 5222-13C, d3 (maleate)

12352005

5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Histamine Receptor; Isotope-Labeled Compounds

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

COVID-19-immunoregulation

Others

[H][C@@]12C3=C(OC4=C([C@]1(CN(C2)[13C]([2H])([2H])[2H])[H])C=CC=C4)C=CC(Cl)=C3.OC(/C=C/C(O)=O)=O

C20 13CH17D3ClNO5

405.85

[1]Shahid M, et al. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol. 2009 Jan;23 (1) :65-73.|[2]Olivia Frånberg, et al. Asenapine, a novel psychopharmacologic agent: preclinical evidence for clinical effects in schizophrenia. Psychopharmacology (Berl) . 2008 Feb;196 (3) :417-29.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W769200/

Isotope-Labeled Compounds

No Development Reported