ASGPR ligand-2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ASGPR ligand-2 (Compound 366) is an asialoglycoprotein receptor (ASGPR) binder. ASGPR ligand-2 can be coupled with recognition elements of target proteins (such as antibodies or antigen-binding fragments), and through the endocytosis mediated by ASGPR, the target protein is delivered to the lysosomes of liver cells, promoting the degradation of the target protein. ASGPR ligand-2 can be used for the research of metabolic disease[1].
3062599-51-0
12352005
LYTACs
PROTAC
Metabolism-protein/nucleotide metabolism
Metabolic Disease
[N-]=[N+]=NCCOCCOCCOCC(NCCOCCC(NCCOCCOCCO[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)NC(C)=O)=O)=O
C27H50N6O14
682.72
[1]Wieslaw Kazmierski, et al. Asgpr binders and compositions and methods thereof. WO2024229005A2. 2025-10-30
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-179737/
Reference compound1
No Development Reported
Beschrijving
ASGPR ligand-2 (Compound 366) is an asialoglycoprotein receptor (ASGPR) binder. ASGPR ligand-2 can be coupled with recognition elements of target proteins (such
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