ASGR1 Antilichaam

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

432

P07306

Human, Mouse, Rat

Recombinant protein of human ASGR1

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 45kDa

IgG

WB: 1:500 - 1:2000

ASGR1

22Rv1

SW620

Mouse liver

Mouse lung

Mouse testis

Asialoglycoprotein receptor 1

Homo sapiens

ASGR1, HL-1, ASGPR, ASGPR1, CLEC4H1

WB

Liquid