ASIC2 Antilichaam

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.

40

Q16515

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human ASIC2 (NP_001085.2) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Neuroscience

Affinity purification

U-251MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 58kDa

IgG

WB: 1:1000 - 1:2000

ASIC2

293T

Mouse brain

Rat brain

Rat lung

Acid-sensing (proton-gated) ion channel 2

Homo sapiens

ACCN1, ACCN, BNC1, MDEG, ACCN1, BNaC1, ASIC2a, hBNaC1

WB

Liquid