ASK1 (Ab 83) Antilichaam

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

4217

Q99683

NP_005914.1

Human

ASK1 (Ab-83) antibody was raised against a peptide sequence around aa.81~85 (G-S-S-V-G) derived from Human ASK1.

Unconjugated

Primary Antibodies

Apoptosis, Cancer

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

155 kDa

This antibody detects endogenous level of total ASK1 protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

MAP3K5

Mitogen-activated protein kinase kinase kinase 5

Homo sapiens

Mabuchi S, et al. (2004) Endocrinology. 145 (1) : 49-58. Yuan ZQ, et al. (2003) J Biol Chem. 278 (26) : 23432-23440. Kim AH, et al. (2001) Mol Cell Biol. 21 (3) : 893-901.

ASK1, MEKK5, MAPKKK5, HER3, ASK-1, M3K5, MAP3K5, MAPK/ERK kinase kinase 5

WB, IHC, IF

5174547

Liquid