[Asp5,6, Me-Phe8] Substance P (5-11)

[Asp5,6, Me-Phe8] Substance P (5-11) is a tachykinin NK-3 receptor agonist. [Asp5,6, Me-Phe8] Substance P (5-11) reduces alcohol intake in genetically selected alcohol-preferring rats[1].

12352209

Neurokinin Receptor

GPCR/G Protein; Neuronal Signaling

Metabolism-protein/nucleotide metabolism

Metabolic Disease

O=C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(C)C=C2)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N

C40H56N8O11S

856.98

[1]Ciccocioppo R, et al. Stimulation of tachykinin NK-3 receptors in the nucleus basalis magnocellularis reduces alcohol intake in rats. Peptides. 1997;18 (9) :1349-55.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11429/

Peptides

No Development Reported

NK3R