ASPCR1 Antilichaam

Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.

79058

Q9BZE9

NP_076988.1

Human

ASPSCR1 antibody was raised against a peptide sequence around aa.303 ~307 (P-Q-Q-E-Q) derived from Human ASPSCR1.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

70 - 75 kDa

This antibody detects endogenous levels of total ASPSCR1 protein.

Western Blot: 1:500~1:1000

ASPSCR1

Alveolar soft part sarcoma chromosome region, candidate 1

Homo sapiens

Ladanyi, M. et al. (2001) Oncogene 20, 48-57. Bogan, J. S. et al. (2003) Nature 425, 727-33. Yu, C. et al. (2007) J Biol Chem 282, 7710-22.

TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1, HSP27, HSP28, TUG

WB

13129078

Liquid