Asperenon

Asperenone is an inhibitor of 15-lipoxygenase (15-LOX) with an IC50 value of 0.3 mM. It is also an inhibitor of platelet aggregation, with an IC50 value of 0.23 mM. Additionally, Asperenone has antifungal activity and can inhibit the growth of pathogenic fungi Ophiostoma crassivaginatum and O. piliferum. Asperenone can be used in the research of cardiovascular diseases and anti-infection fields[1].

18810-05-4

12352005

Fungal; Lipoxygenase

Anti-infection; Metabolic Enzyme/Protease

Infection; Cardiovascular Disease

CCC(/C=C/C=C/C(C)=C/C=C/C=C/C1=CC=CC=C1)=O

C20H22O

278.39

[1]Sekhar Rao K C, et al. Asperenone: an inhibitor of 15-lipoxygenase and of human platelet aggregation from Aspergillus niger[J]. Biotechnology letters, 2002, 24: 1967-1970.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15453/

Natural Products

No Development Reported

15-LOX