Aspergillusidon D

Aspergillusidone D (Compound 1), a brominated depsidone, is a Aromatase inhibitor with an IC50 of 0.8 μM. Aspergillusidone D can be isolated from fungus Aspergillus unguis cultured in KBr medium. Aspergillusidone D has potent cytotoxicity against cancers cells, such as MOLT-3 cells. Aspergillusidone D can be used for cancers like breast cancer research[1].

1454585-77-3

12352005

Cytochrome P450; Endogenous Metabolite

Metabolic Enzyme/Protease

Cancer

C/C=C(C1=C2C(OC(C3=C(C)C(Br)=C(O)C=C3O2)=O)=C(C(O)=C1Br)C)\C

C19H16Br2O5

484.14

[1]Sureram S, et al. Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis[J]. RSC advances, 2013, 3 (6) : 1781-1788.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N16402/

Natural Products

No Development Reported

Aromatase/CYP19A1