AStAx-35R
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1418863-17-8
Wnt/beta-catenin
Stem Cells, Cytoskeletal Signaling
AStAx-35R is a stapled peptide that antagonizes the nuclear form of β-catenin, thereby inhibiting Wnt signaling. It competitively inhibits the binding of β-catenin to TCF4. Additionally, aStAx-35R selectively induces growth inhibition in Wnt-dependent cancer cells.
C([C@@H](C(=O)N1[C@H](C(N[C@H](C(N[C@]2(C)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=4C=5C(NC4)=CC=CC5)C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)=O)C(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)[C@@H](C)C)=O)=O)(C)CCCC=CCCC2)[H])=O)CCCNC(=N)N)=O)CCC1)NC([C@@H](NC([C@H](CCCNC(=N)N)NC(C)=O)=O)CCCNC(=N)N)=O)C=6C=7C(NC6)=CC=CC7
C111H178N40O20
2392.86
Ice Packs
-20°C
Beschrijving
AStAx-35R Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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