ATG16L1 Antilichaam - middengebied: FITC (ARP54272_P050-FITC)

ATG16 autophagy related 16-like 1 (S. cerevisiae)

IBD10, WDR30, APG16L, ATG16A, ATG16L

55054

Q676U5

NP_110430

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human ATG16L1

Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]) .[supplied by OMIM].

WIPI2; RB1CC1; DEDD2; TRAF3IP3; NOD2; TMEM59; TLR2; SUMO2; ATG13; ATG5; ULK1; UBC; TNK2; SYNPO2; ATG12; NOD1; WDFY3; APP; RAB33B; RAB35; RAB3D; RAB33A; HSPA4; FCGRT; CLTC; AP2M1; ELAVL1; MAP1LC3C; MAP1LC3B; ATG3; CCT2; CCT7; AGPS; GAN; CCT3; SNAPC4; ATG16

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

68kDa

Hancock, L., (er) Inflamm. Bowel Dis. (2008) In press

Wet Ice

607

ATG16L1

ATG16L1

Rabbit

Autophagy-related protein 16-1

NM_030803

TSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPG