ATG4B Mouse Monoclonal Antibody [Kloon ID: LBI1A3]

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) ATG4B mouse monoclonal antibody, clone LBI1A3

APG4B; AUTL1

Homo sapiens autophagy related 4B cysteine peptidase (ATG4B), transcript variant 2, mRNA.

23192

Q9Y4P1

Unconjugated

Regulation of autophagy

Regulation of autophagy

WB 1:500~2000, IHC 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Protease

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

ATG4B

https://www.ncbi.nlm.nih.gov/gene/?term=23192

https://www.uniprot.org/uniprot/Q9Y4P1