ATG5 Antilichaam - middengebied: HRP (ARP59071 P050-HRP)

ATG5 autophagy related 5 homolog (S. cerevisiae)

ASP, APG5, APG5L, hAPG5, SCAR25, APG5-LIKE

9474

Q9H1Y0

NP_004840

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human ATG5

ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.

TEKT4; CCHCR1; WIPI2; KEAP1; VCP; MEOX2; FADD; ATG16L1; RB1CC1; EXOC4; ATG3; ATG12; CAV1; HTT; WDFY3; TAB3; TAB2; TECPR1; ELAVL1; UBC; SIRT1; TKT; MAP1LC3C; MAP1LC3B; ATG10; ATG5; IMPDH2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 79%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32kDa

Wet Ice

275

ATG5

ATG5

Rabbit

Autophagy protein 5

NM_004849

RFDQFWAINRKLMEYPAEENGFRYIPFRIYQTTTERPFIQKLFRPVAADG