ATIC-IN-2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ATIC-IN-2 (Compound 1) is a competitive inhibitor for the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), that binds to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM[1].
67095-44-7
12352005
H302, H315, H319, H335
DNA/RNA Synthesis
Cell Cycle/DNA Damage
Cancer
10mM
98.0
DMSO : ≥ 50 mg/mL
O=C1NS(=O)(NC2=C1NC=N2)=O
C4H4N4O3S
188.17
H302, H315, H319, H335
[1]Xu L, et al., Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase. J Biol Chem. 2007 Apr 27;282 (17) :13033-46.
Room Temperature
Store at room temperature 3 years
http://file.medchemexpress.com/batch_PDF/HY-29244/ATIC-IN-2-SDS-MedChemExpress.pdf
Reference compound1
No Development Reported
Beschrijving
ATIC-IN-2 (Compound 1) is a competitive inhibitor for the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), that binds to inosine monophosphate cyclohydrolase (IMPC
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