Atigotatug (FUT8-KO)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Atigotatug (FUT8-KO) is an anti-fuc-GM1 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out, and fucose deficiency enhances the ADCC effect of the antibody. Atigotatug is a Fucosyl ganglioside GM1 (fuc-GM1) -targeting IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as small cell lung cancer[1].
2733581-82-1
BMS-986012 (FUT8-KO)
12352203
Others
Others
Cancer
[Atigotatug(FUT8-KO)]
[1]Paz-Ares L G, et al. The TIGOS trial: A randomized, double-blind phase 3 trial of atigotatug+ nivolumab fixed-dose combination with chemotherapy vs atezolizumab with chemotherapy in patients with 1L extensive-stage small cell lung cancer (ES-SCLC) [J]. 2025.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P990902A/
Inhibitory Antibodies
No Development Reported
Beschrijving
Atigotatug (FUT8-KO) is an anti-fuc-GM1 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out, and fucose deficiency
Specificaties
Recent bekeken producten
Human Mast Cells - Dermis
ABC-TC105W
1 Vial
CYP1A2 Inhibitor Screening Assay
MA-0389
200 Well
Culture Medium for Immortalized Human Parathyroid Cells
AFG-ELL-2645-01
100 mL
Immortalized Human Parathyroid Cells
AFG-ELL-2055
> 1x 10^6 Cells / Vial
1,4- Dioxane Pure
1041330 500
500 mL
EPS8 Antibody (N-term) [APR32555G]
APR32555G-01
50 µL
Prestained Protein Ladder (25-300 kDa)
CRG1114
250 µL
Rat IgG Lyophilized
B2013903
25 mg
Recent gezochte producten
Hsa-miR-1258 mimic
HY-R00162-01
5 nmol
Hsa-miR-4258 mimic
HY-R00937-01
5 nmol
hsa-miR-1258 miRNA Mimic
MBS8298831-01
5 nmol
hsa-miR-4258 miRNA Mimic
MBS8299087-01
5 nmol
hsa-miR-1258 miRNA Agomir
MBS8311479-01
5 nmol
Hsa-miR-1258 miRNA Mimic
CMH0784-01
5 nmol
Hsa-miR-4258 miRNA Mimic
CMH1040-01
5 nmol
Hsa-miR-4258 miRNA Agomir
CMJ1040-01
5 nmol