ATP-13C2 (dilithium)

ATP-13C2 (Adenosine 5'-triphosphate-13C2) dilithium is 13C-labeled ATP. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

Adenosine 5'-triphosphate-13C2 (dilithium)

12352005

Endogenous Metabolite; Isotope-Labeled Compounds

Metabolic Enzyme/Protease; Others

Metabolic Disease; Inflammation/Immunology

100 mM in 19.19 μL Tris HCl/H2O buffer pH=7.5

96.0

O[C@H]([C@H](O1)CO[P](O[P](O[P](O)(O[Li])=O)(O[Li])=O)(O)=O)[C@@H](O)[C@@H]1N2C3=N[13CH]=NC(N)=C3N=[13CH]2

C8 13C2H14Li2N5O13P3

521.03

[1]Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35 (3) :852-8. |[2]M J L Bours, et al. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112 (2) :358-404. |[3]Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov;107:104514. |[4]Yang Xiang, et al. Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013; 8 (5) : e63759.

Blue Ice

Solution, -20°C, 2 years

http://file.medchemexpress.com/batch_PDF/HY-B2176S7/ATP-13C2-dilithium-SDS-MedChemExpress.pdf

Isotope-Labeled Compounds

No Development Reported