ATP1A2 Antilichaam

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood.

477

P50993

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ATP1A2 (NP_000693.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 112kDa

IgG

WB: 1:500 - 1:2000

ATP1A2

OVCAR3

Mouse heart

Mouse lung

Mouse testis

Rat heart

ATPase Na+/K+ transporting subunit alpha 2

Homo sapiens

FHM2, MHP2, sodium/potassium-transporting ATPase subunit alpha-2, ATPase Na+/K+ transporting alpha 2 polypeptide, Na (+) /K (+) ATPase alpha-2 subunit, Na+/K+ ATPase, alpha-A (+) catalytic polypeptide, Na+/K+ ATPase, alpha-B polypeptide, sodium pump subunit alpha-2, sodium-potassium ATPase catalytic subunit alpha-2, sodium/potassium-transporting ATPase alpha-2 chain

WB

Liquid