ATP5A1 Antilichaam

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c) . This gene encodes the alpha subunit of the catalytic core.

498

P25705

P25705

Human

This ATP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-503 amino acids from the C-terminal region of human ATP5A1.

Unconjugated

Primary Antibodies

Obesity, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

60 kDa

Rabbit Ig

ATP5A1

ATP synthase subunit alpha, mitochondrial

Homo sapiens

Pandey, N.R., et al. Am. J. Pathol. 175 (4) :1777-1787 (2009)

Seth, R., et al. J. Clin. Pathol. 62 (7) :598-603 (2009)

Law, I.K., et al. Proteomics 9 (9) :2444-2456 (2009)

Martins-de-Souza, D., et al. BMC Psychiatry 9, 17 (2009)

ATP synthase subunit alpha, mitochondrial, ATP5A1, ATP5A, ATP5AL2, ATPM

WB, IHC-P

114517

Liquid