ATP6V0C Antilichaam - middelste regio : HRP (ARP45161_P050-HRP)

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

ATPL, VATL, VPPC, Vma3, ATP6C, ATP6L

527

P27449

NP_001685

Human, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the middle region of human ATP6V0C

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the V0 domain. This gene had the previous symbols of ATP6C and ATP6L.

SMIM3; UBC; PSMA3; MSR1; EDA; CERS2; CLIC1; RNF182; MARK3; ARF6

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

ATP6V0C is strongly supported by BioGPS gene expression data to be expressed in ACHN, OVCAR3

0.5 mg/ml

Cow: 86%; Dog: 86%; Horse: 93%; Human: 100%; Pig: 79%; Rabbit: 86%; Rat: 90%; Sheep: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

16kDa

Wet Ice

155

ATP6V0C

ATP6V0C

Rabbit

V-type proton ATPase 16 kDa proteolipid subunit

NM_001694

VVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRG