ATP7A Antilichaam

ATPase, Copper-transporting, α polypeptide; Copper-transporting ATPase 1. Copper-transporting ATPase 1 is an integral membrane protein cycling constitutively between the trans-golgi network and the plasma membrane. It may supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.

538

Q04656

NP_000043.1

Human, Mouse, Rat

1407-1500

Unconjugated

Primary Antibodies

Innate Immunity, Signal Transduction

Antigen affinity-purified

1 mg/mL

Phosphate-Buffered Saline. No preservatives added.

None

Blue Ice

ATP7A antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

163.3 kDa (calculated)

ATP7A antibody can be used for the detection of ATP7A by Western blot, may also work for IHC and ICC.

ATP7A

ATPase, Cu++ transporting, alpha polypeptide

Homo sapiens

Vulpe, C., Levinson, B., Whitney, S., Packman, S. and Gitschier, J. Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase Nat. Genet. 3 (1), 7-13 (1993) .

MC1, MNK, Copper-transporting ATPase 1, Copper pump 1, MK, DSMAX, SMAX3

WB

4502321

Liquid