Attractin Polyklonal Antibody, AbBy FluorTM 405 Vervoeging

Attractin is a serum glycoprotein of 175 kDaand found in both membrane-bound and secreted forms as a result of alternative splicing. Both the secreted and membrane-bound forms of attractin may be involved in the development and maintenance of the central nervous system. Membrane-bound attractin is a co-receptor for Agouti, antagonist of melanocortin-1 receptor. Secreted attractin, expressed by activated T lymphocytes and modulates interactions between T cells and monocytes/macrophages, was examined as a potential marker of immune activity. Attractinmay be a component of a pathway for regulated protein turnover that also involves mahogunin, a wide-expressed E3 ubiquitinligase found at particularly high levels in the brain. Attractinwas considered as an extracellular target amenable for the development of obesity-regulating drugs, also.

ATRN; attractin-2; DPPT-L; KIAA0548; Mahogany homolog; mahogany protein; MGCA.

8455

Secreted, Cell membrane

Human, Mouse

751-850/1429

Attractin

AbBy Fluor™ 405

KLH conjugated synthetic peptide derived from human ATRN

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

401nm/421nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

8455

Rat, Dog, Pig, Rabbit