Attractin Polyklonal Antibody, Biotin Conjugated

Mahogany (MG), originally identified as a protein involved in pigmentation, acts in conjunction with melanocortin receptors to suppress diet-induced obesity. Mahogany contains a single transmembrane domain, and it is expressed in a broad range of tissues, including the hypothalamus and pigment cells. Mutations within the mahogany gene were shown to rescue agouti-lethal-yellow mutant mice from obesity. The extracellular domain of mouse mahogany is the ortholog of the human protein attractin. Attractin (also designated DPPT-L) is a human serum glycoprotein and is a member of the CUB family of cell adhesion and guidance proteins. Attractin is expressed on activated T cells and is released from the cells 48 to 72 hours after activation.

ATRN; ATRN_HUMAN; attractin 2; Attractin; attractin-2; DPPT L; DPPT-L; KIAA0548; Mahogany homolog; mahogany protein; MGCA.

8455

Secreted, Cell membrane

1201-1300/1429

Attractin

Biotin

KLH conjugated synthetic peptide derived from human Attractin

ELISA, IHC-P, IHC-F

Purified by Protein A.

1µg/µl

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C for 12 months.

8455

Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Rabbit