AURKA Antibody - C-terminal regio : HRP (ARP30876 P050-HRP)

Aurora kinase A

AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, PPP1R47

6790

O14965

NP_003591

Human, Cow, Sheep

The immunogen is a synthetic peptide directed towards the C terminal region of human AURKA

AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

CHFR; GADD45A; RPLP2; RPLP0; RPL38; RPL30; RPL27; RPL22; RPL12; RPL11; PSMB7; PSMB5; PSMA6; PSMA5; PSMA1; MAPK6; PPP6C; PCMT1; YBX1; NPM1; NCL; MFAP4; LYZ; ILF3; ILF2; IARS; HSPD1; HSP90AB1; HSP90AA1; HSPA9; HSPA8; HSPA5; HSPA2; HSPA1A; HNRNPU; HNRNPA2B1

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

There is BioGPS gene expression data showing that AURKA is expressed in HEK293T

0.5 mg/ml

Cow: 80%; Human: 100%; Sheep: 80%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

46kDa

Ye, Y., (2008) Cancer 112 (11), 2467-2474

Wet Ice

403

AURKA

AURKA

Rabbit

Aurora kinase A

NM_003600

ARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS