AURKC Antilichaam

Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100

Q9UQB9

Human

A portion of the C-terminal region of the human protein was used as immunogen for this AURKC antibody.

WB, IHC, ELISA

Purified

Purified

This AURKC antibody is available for research use only.

Aliquot the AURKC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

Titration of the AURKC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Western blot testing of AURKC antibody and A375 cell lysate. Predicted molecular weight ~ 33 kDa.