Avapritinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1703793-34-3
BLU-285
C13489-2mg
PDGFR
Protein Tyrosine Kinase
CC (C1=CC=C (C=C1) F) (C2=CN=C (N=C2) N3CCN (CC3) C4=NC=NN5C4=CC (=C5) C6=CN (N=C6) C) N
C26H27FN10
Avapritinib is a small molecule kinase inhibitor that potently inhibits PDGFRα D842V mutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM) ; also a potent inhibitor of the analogous Kit (c-Kit) mutation, D816V in Kit (c-Kit) Exon 17 (IC50 = 0.5 nM) .
2 years -80 in solvent
Beschrijving
Avapritinib Beschikbaar in 2 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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