Avenanthramide C

116764-15-9

AMPK, IL Receptor, Bcl-2 Family, Caspase, Interleukin, TNF, Adrenergic Receptor

GPCR/G Protein, PI3K/Akt/mTOR signaling, Apoptosis, Neuroscience, Proteases/Proteasome, Immunology/Inflammation, Chromatin/Epigenetic

0.994

Avenanthramide C is an orally available natural alkaloid with antioxidant/inflammatory properties that reduces the expression of TNF-a, BAK, IL-1b, and Bcl-2; reverses memory and behavioral deficits in Alzheimer's disease, with a reduction in caspase-3 cleavage and an increase in levels of pS9GSK-3β and IL-10, is able to bind α1A adrenergic and stimulate AMPK; can attenuate noise and drug-induced hearing loss.

N(C(/C=C/C1=CC(O)=C(O)C=C1)=O)C2=C(C(O)=O)C=C(O)C=C2

C16H13NO6

315.28

Ice Packs

-20°C