Avermectine B2a

Avermectin B2a is an insecticide targeting glutamate-gated chloride channels (GluCls) . Avermectin B2a causes hyperpolarization of nematode/insect neurons and subsequent paralysis/death. Avermectin B2a is promising for research of agricultural pests[1].

65195-57-5

12352005

H301

Chloride Channel; Insecticide; Parasite

Anti-infection; Membrane Transporter/Ion Channel; Others

Infection

CC[C@@H]([C@@]1([H])O[C@]2(C[C@@H]([C@@H]1C)O)C[C@]3([H])C[C@](C/C=C([C@H]([C@H](/C=C/C=C4[C@]5([C@](C=C([C@H]([C@@]5([H])OC/4)O)C)([H])C(O3)=O)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)([H])O2)C

C48H74O15

891.09

P264-P270-P330-P405-P501

[1]Gao C, et al. Two new avermectin derivatives from the Beibu Gulf gorgonian Anthogorgia caerulea. Chem Biodivers. 2014 May;11 (5) :812-8.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-Z8942/

Reference compound2

No Development Reported