Avitinibmaleaat
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1557268-88-8
Abivertinib maleate, AC0010 maleate, AC0010MA
EGFR
Protein Tyrosine Kinase
C26H26FN7O2.C4H4O4
Avitinib maleate (Abivertinib maleate, AC0010 maleate, AC0010MA) is a third-generation, irreversible, and orally active selective inhibitor of EGFR. It displays IC50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R, EGFR T790M, and wild-type EGFR. Avitinib maleate also acts as an inhibitor of BTK that induces apoptosis of BTK in mantle cell lymphoma.
Beschrijving
Avitinibmaleaat Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.
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