Axitrirom
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Axitirome (CGS 26214) is a potent, liverselective TRβ receptor agonist and thyromimetic agent. Axitirome has demonstrated cholesterol-lowering activity[1].
156740-57-7
CGS 26214
12352005
H302-H372-H411
Thyroid Hormone Receptor
Vitamin D Related/Nuclear Receptor
Metabolic Disease
O=C(OCC)C(NC1=CC(C)=C(OC2=CC=C(O)C(C(C3=CC=C(F)C=C3)O)=C2)C(C)=C1)=O
C25H24FNO6
453.46
P260-P264-P273-P391-P501
[1]Wu R, et al. Conferring liver selectivity to a thyromimetic using a novel nanoparticle increases therapeutic efficacy in a diet-induced obesity animal model. PNAS Nexus. 2023 Aug 29;2 (8) :pgad252.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19201/
Reference compound1
Phase 1
Beschrijving
Axitirome (CGS 26214) is a potent, liverselective TRβ receptor agonist and thyromimetic agent. Axitirome has demonstrated cholesterol-lowering activity[1].
Specificaties
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