
Az-NC-002
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Az-NC-002 is a Proteasome trypsin-like site (β2) and immunoproteasome β2i-specific active probe. Az-NC-002 has weak off-target effects with no significant inhibition for Cathepsin D , but this inhibition reacts outside of the active site or influence on a small fraction of the enzyme[1].
1356828-49-3
12352209
Proteasome
Metabolic Enzyme/Protease
Others
[N-]=[N+]=NCC(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C([C@]1(CO1)C)=O)=O)=O)=O
C23H41N9O5
523.63
[1]Mirabella AC, et al. Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib. Chem Biol. 2011 May 27;18 (5) :608-18.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P11331/
Peptides
No Development Reported
Beschrijving
Az-NC-002 is a Proteasome trypsin-like site (β2) and immunoproteasome β2i-specific active probe. Az-NC-002 has weak off-target effects with no significant inhib
Specificaties
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