
AZ7550 Mesylaat (Standaard)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
AZ7550 Mesylate (Standard) is the analytical standard of AZ7550 Mesylate. This product is intended for research and analytical applications. AZ7550 Mesylate is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6 μM.
2319837-99-3
AZ7550 trimesylate salt (Standard)
12352005
Drug Metabolite; EGFR; IGF-1R; Reference Standards
JAK/STAT Signaling; Metabolic Enzyme/Protease; Others; Protein Tyrosine Kinase/RTK
Cancer; Endocrinology
CN1C=C(C2=NC(NC3=CC(NC(C=C)=O)=C(N(CCNC)C)C=C3OC)=NC=C2)C4=CC=CC=C41.O=S(O)(C)=O.O=S(O)(C)=O.O=S(O)(C)=O
C30H43N7O11S3
773.90
[1]Finlay MR, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57 (20) :8249-67.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-B0794BR/
Reference Standards
Beschrijving
AZ7550 Mesylate (Standard) is the analytical standard of AZ7550 Mesylate. This product is intended for research and analytical applications. AZ7550 Mesylate is
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