Azaspireen
Gecertificeerd

Azaspireen

Catalog #: HY-N15264
Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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BTW niet inbegrepen
Gratis verzending vanaf €100

Technische Specificaties

Description

Azaspirene ((-) -Azaspirene) is an angiogenesis and Raf-1 activation inhibitor isolated from the fungus Neosartorya sp. Azaspirene inhibits vascular endothelial growth factor (VEGF) -induced human umbilical vein endothelial cell (HUVEC) migration and Raf-1 activation, but has no effect on the activation of kinase insert domain-containing receptor/fetal liver kinase 1 (VEGF receptor 2) [1].

CAS Number

461644-34-8

Product Name Alternative

(-) -Azaspirene

UNSPSC

12352005

Target

Raf; VEGFR

Related Pathways

MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

O[C@@H]1[C@]2(C(N[C@@]1(O)CC3=CC=CC=C3)=O)OC(/C=C/C=C/CC)=C(C2=O)C

Molecular Formula

C21H23NO5

Molecular Weight

369.41

References & Citations

[1]Asami Y, et al. Azaspirene, a fungal product, inhibits angiogenesis by blocking Raf-1 activation. Cancer Sci. 2008 Sep;99 (9) :1853-8.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N15264/

Scientific Category

Natural Products

Clinical Information

No Development Reported

Beschrijving

Azaspirene ((-) -Azaspirene) is an angiogenesis and Raf-1 activation inhibitor isolated from the fungus Neosartorya sp. Azaspirene inhibits vascular endothelial

Specificaties

ProductnaamAzaspireen
Categorie
Beschikbare grootte1 Each
CatalogusnummerHY-N15264