
AZD5153 6-hydroxy-2-sulfonzuur
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1869912-40-2
AZD5153 HNT salt
C13358-5mg
Epigenetic Reader Domain
Epigenetics
CC1C (=O) N (CCN1CCOC2=CC=C (C=C2) C3CCN (CC3) C4=NN5C (=NN=C5OC) C=C4) C.C1=CC2=C (C=CC (=C2) O) C=C1C (=O) O
C25H33N7O3.C11H8O3
AZD5153 6-hydroxy-2-naphthoic acid (HNT salt) is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor with pKi of 8.3 for BRD4. AZD5153 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes. NSD3, via H3K36me2, acts as an epigenetic deregulator to facilitate the expression of oncogenesis-promoting genes.
2 years -80 in solvent
Beschrijving
AZD5153 6-hydroxy-2-sulfonzuur Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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