AZD7648
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
AZD7648 is a very potent and selective (against 397 kinases) DNA-PK inhibitor (pIC50 = 9.2; cellular pIC50 = 7.0) .1 It is a sensitizer of radiation- and doxorubicin-induced DNA damage and sustained tumor regression in xenograft and patient-derived xenograft models.2 AZD7648 significantly enhances precise CRISPR/Cas9 gene editing alone3,4,5 or in combined treatment with a DNA polymerase theta inhibitor (2iHDR cocktail) 5.
Unconjugated
White solid
-20°C
Beschrijving
AZD7648 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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