AZD8421
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
3047321-53-6
CDK
Cell Cycle
C18H32N8O3S
AZD8421 is a potent and highly selective inhibitor of Cyclin-dependent Kinase 2 (CDK2), with an IC50 against CDK2 of 9nM with selectivity over CDK1, CDK4 and CDK6. It also exhibits an anti-proliferative effect, effectively inhibits Rb phosphorylation, and shows strong activity both as a monotherapy and in combination with CDK4/6 inhibitors in breast and ovarian cancer models.
Beschrijving
AZD8421 Beschikbaar in 1 g. Bestel eenvoudig online met snelle levering.
Specificaties
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