Azido-PEG8-Amido-Val-Cit-PAB
Gecertificeerd

Azido-PEG8-Amido-Val-Cit-PAB

Catalog #: TYD-01874-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

Technische Specificaties

CAS Number

2356229-77-9

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker efficiently cleaved by cathepsin B. Since cathepsin B is localized in lysosomes, the ADC payload is released exclusively within cells. The azido group reacts with DBCO, BCN, or other alkyne groups through click chemistry. The PEG spacer enhances water solubility. Reagent grade, intended for research purposes.

Smiles

N(C([C@@H](NC([C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C1=CC=C(CO)C=C1

Molecular Formula

C40H69N9O15

Molecular Weight

916.027

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

Azido-PEG8-Amido-Val-Cit-PAB Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamAzido-PEG8-Amido-Val-Cit-PAB
Categorie
Beschikbare grootte10 mg
CatalogusnummerTYD-01874-01