Azido-PEG8-Amido-Val-Cit-PAB
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Azido will react with DBCO, BCN or other alkyne groups through click chemistry. PEG spacer increases aqueous solubility. Reagent grade, for research purpose.
2356229-77-9
12352203
ADC Linker
Antibody-drug Conjugate/ADC Related
Cancer-programmed cell death
Cancer
[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)=O)=O
C40H69N9O15
916.03
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W800814/
ADC Related
No Development Reported
Beschrijving
Azido-PEG8-Amido-Val-Cit-PAB is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome,
Specificaties
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
MSP-12X20
1 Unit
MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NOR-30
1 Unit
MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRC-3001
1 Unit
MS pipette, variable vol µme 1000~10000 µL
MSP-10000
1 Unit