B-cel CLL/lymfoom 2 Adenovirus (Ad-BCL2)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Members of the Bcl-2 family of proteins interact to regulate programmed cell death (apoptosis) . Various homodimers and heterodimers formed by proteins in this family either promote or inhibit apoptosis. Pro-apoptotic members of this family include Bax, Bcl-xS, Bad, Bak, NBK (Bik), BID, Hrk, Bok, Bim, NOXA, Diva and Bmf. Apoptotic inhibitors include Bcl-2, Bcl-xL, Bcl-x (beta), Bcl-x (gamma), Bcl-w, Mcl-1, Bag-1, A1 (Bfl-1), BAR and BI-1 (TEGT) . Bok, or Bcl-2 related ovarian killer, induces apoptosis in cells, but is suppressed by anti-apoptotic Bcl-2 family proteins. BECN1 plays a significant role in autophagy. PUMA gene encodes two BH3 domain-containing proteins PUMA (alpha) and PUMA (beta), which have similar binding activities to Bcl-2, localize to the mitochondria to induce cytochrome c release and activate the rapid induction of programmed cell death.
B-cell CLL/lymphoma 2 Adenovirus
41106621
3822190000
Pre-Made
Dry Ice
-80C
12 Months
Ad-BCL2
Human Adenovirus Type5 (dE1/E3)
CMV (ubiquitous)
DMEM, 2% BSA, 2.5% Glycerol
1x10^10 PFU/ml
Beschrijving
Members of the Bcl-2 family of proteins interact to regulate programmed cell death (apoptosis) . Various homodimers and heterodimers formed by proteins in this
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